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Home > Products >  Safe Shipping good Calcitriol powder CAS NO.32222-06-3

Safe Shipping good Calcitriol powder CAS NO.32222-06-3 CAS NO.32222-06-3

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  • FOB Price: USD 1600 /Kilogram Get Latest Price
  • Min.Order: 10 Gram
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Keywords

  • Best price of Calcitriol powder
  • high purity of 1α,25-Dihydroxyvitamin D3
  • 1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol factory

Quick Details

  • ProName: Safe Shipping good Calcitriol powder C...
  • CasNo: 32222-06-3
  • Molecular Formula: C27H44O3
  • Appearance: white powder
  • Application: CAS 32222-06-3
  • DeliveryTime: 15 days
  • PackAge: 25 KG / PP bag
  • Port: Tianjin
  • ProductionCapacity: 1000 Metric Ton/Month
  • Purity: 99%
  • Storage: dry place
  • Transportation: By shipment
  • LimitNum: 10 Gram
  • Moisture Content: 0
  • Impurity: 0
  • 0: 0

Superiority

 
calcitriol,cas :32222-06-3
 
 
 
 
 
(1r,3s,5z)-5-[(2e)-2-[(1r,3as,7ar)-1-[(2r)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; 1α,25-dihydroxyvitamin d3; 1,25-dihydroxycholecalciferol;

Details

details

calcitriol

cas no:32222-06-3 
mf:c27h44o3 
use:osteoporosis 
appearance:white powder

product name

calcitriol

5z,7e) -9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol

batch no.

my3090514

 

retest date

apr. 2011

quantity

5g

manu. date

may 2009

cas no.

32222-06-3

..2006

ref. standard

usp32

 

items

specifications

test results

appearance

white powder

conform

solubility

corresponds

corresponds

identification

ir

hplc the principal peak in the chromatogram obtained with the test solution is similar in retention time and size to the principal peak in the chromatogram obtained with stand solution

conform

conform

 

 

 

 

purity

tlc: one spot

hplc:99.0%

one spot

99.7%

related impurities

triazoline adduct of pre-isomer: 0.1%max

trans-isomer: 0.25max

1β-isomer:0.1%max

methylene isomer: 0.1%max

 

not detected

0.07%

not detected

0.06%

an other single related substance apart from pre-calcitriol

0.1%max

0.06%

total impurities

1.0%max

0.3%

unknown imp each

0.1%max

conform

content

97.0~103.0%

 

calcitriol basic information
toxicity grading flammability and hazard characteristics extinguishing agent
product name: calcitriol
synonyms: vitamin d3, 1alpha,25-dihydroxy;(5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol;9,10-secocholesta-5z,7e,10(19)-triene-1alpha,3beta,25-triol;1,25-(oh)2-d3;(1alpha,3beta,5z,7e)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol;1alpha,25-dihydroxycholecalciferol;1alpha,25-dihydroxyvitamin d3;1alpha,25-dihydroxy-vitamin d8
cas: 32222-06-3
mf: c27h44o3
mw: 416.64
einecs: 250-963-8
product categories: miscellaneous biochemicals;vitamin d3 analogs;api;chiral reagents;intermediates & fine chemicals;pharmaceuticals;isolabel;reagent;standard substance;inhibitors
mol file: 32222-06-3.mol
calcitriol structure
 
calcitriol chemical properties
mp 119-1210c
fp 14 °c
storage temp. 2-8°c
stability: air and light sensitive
cas database reference 32222-06-3(cas database reference)
 
safety information
hazard codes t+,xn,f
risk statements 26/27/28-63-36/37/38-20/21/22-11
safety statements 36/37/39-45-36-26-16-7
ridadr un 2811 6.1/pg 1
wgk germany 3
rtecs fz4645000
f 8-10-19
hazardclass 6.1(a)
packinggroup i
hs code 29061900
hazardous substances data 32222-06-3(hazardous substances data)
msds information
provider language
1alpha,25-dihydroxycholecalciferol english
sigmaaldrich english
 
calcitriol usage and synthesis
physiological function calcitriol is the active form of vitamin d and is also a kind of hormones in the body. it plays an important role in the regulation of calcium and phosphorus concentration. it can increase the blood calcium level by increasing the intestinal absorption of calcium and can also increase the release of the bone calcium release for increasing the blood calcium levels. this study was first conducted and reported by michael f. holick in 1971. the basic principle of action model of calcitriol in many cases is through binding with the vitamin d receptor (the vdr), e.g., the ligand-receptor complex forming between calcitriol and its receptor in the intestinal epithelial cells cytoplasm can be transferred to the nucleus for being as the transcriptional factor in promoting the expression of calcium-binding protein. the increased level of calcium-binding proteins can help the cell to actively transport of more calcium ions, thereby increasing the calcium absorption level. calcium absorption while maintaining electrical neutrality also requires transporting anions, mainly the absorption of inorganic phosphate ions, so calcitriol also promote the absorption of phosphorus. 
clinically, this drug can be used in the treatment of hypocalcemia, hypoparathyroidism (adult), osteomalacia, rickets (infants), chronic kidney disease, renal osteodystrophy, osteoporosis, as well as the prevention of glucocorticoid induced osteoporosis.
calcitriol-dimensional molecular structure
calcitriol-dimensional molecular structure
the above information is edited by the chemicalbook of dai xiongfeng.
application vitamin medicines; it can be used for treating the renal bone malnutrition of patients with chronic renal failure;
category toxic substances
toxicity grading highly toxic
acute toxicity oral - rat ld50 0.62 mg / kg; oral - mouse ld50: 1.35 mg / kg
flammability and hazard characteristics flammable with the fire releasing acrid smoke
storage characteristics treasury: ventilation, low-temperature and drying; store it separately from food
extinguishing agent water, sand
chemical properties white crystalline powder
usage the biologically active form of vitamin d3. calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic
usage calcium regulator, anti-psoriatic
biological activity active metabolite of vitamin d 3 that activates the vitamin d receptor (vdr). displays calcemic actions; stimulates intestinal and renal ca 2+ absorption and regulates bone ca 2+ turnover. exhibits antitumor activity; inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.

 

 

 

 

packaging & delivery:

1. mass stock: to make sure delivery promptly every day when the payment is done.
2. rich experience: we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.
3. professional team: well-trained and disciplined team which is professional enough to provide you a safe package. unique ways to ship 10 grams to 20 kilograms powders (or 100ml to 30 liter liquids) at one time to your destination.
4. logistics information:packing pics and tacking number are provided within 12 hours after we confirm your payment. updated tracking information will be provided every other day just for you can hold a palm of your package.
5. perfect after-sale service: any questions or problems after receiving the product, please feel free to contact us. problems would be solved immediately.

 

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200% supporting re-sending policy

 

 

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packaging & delivery:

1. mass stock: to make sure delivery promptly every day when the payment is done.

2. rich experience: we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.

3. professional team: well-trained and disciplined team which is professional enough to provide you a safe package. unique ways to ship 10 grams to 20 kilograms powders (or 100ml to 30 liter liquids) at one time to your destination.

4. logistics information:packing pics and tacking number are provided within 12 hours after we confirm your payment. updated tracking information will be provided every other day just for you can hold a palm of your package.

5. perfect after-sale service: any questions or problems after receiving the product, please feel free to contact us. problems would be solved immediately.

 
 

quality control system

we do strict quality control in whole production process. all unqualified products are rejecting before shipping.

 

production capacity

we can produce both natrual extraction and chemical synthesis

logistics capacity

we can deliver goods by sea, air and express.

after-sales service(re-call)

certification

 

plant base

workshop

raw material warehouse

 

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